Skip to Main Content

Evidence Synthesis

A guide to systematic reviews and evidence synthesis methods

Evidence Synthesis Reviews comparison chart


There are many types of evidence synthesis reviews. The most common are systematic reviews, meta-analyses, and scoping reviews, but depending on your research needs, a different type of review may be best for you. The chart below compares multiple review types, and there are also tools available to help you decide on the best review type for your work.

Evidence Synthesis Review Types
Type of review Description Search method Appraisal of Quality Synthesis Analysis
Critical Review

Critically evaluates research in a specific area - its effectiveness and quality;

Typically results in a hypothesis or model rather than an answer to a question

Extensive search aims to identify the most significant and impactful sources

No formal quality appraisal required;

Evaluation is based on the contribution of each source

Typically narrative; may be conceptual or chronological

Incorporates significant analysis using criteria such as strengths, weaknesses, or validity of cited sources;

Identify level of significance, contribution of sources to an overall concept, or derive new theory

Integrative Review Evaluates and integrates both empirical and theoretical studies to address a clinical (or other) problem Comprehensive and exhaustive search required Formal quality appraisal required Tables, narrative Identify patterns and themes among sources and provide recommendations for practice and/or future research
Literature Review

A generic term;

Provides a broad overview of a research area or describes literature on a topic to summarize what has been accomplished or identify gaps. Not comprehensive in nature

Comprehensive search not required;

No formal criteria for selecting relevant resources

No formal quality appraisal required Typically narrative Analysis may be chronological, conceptual, thematic, etc.
Mapping review / Evidence or Gap Map

Map out and classify quality and quantity of existing studies on a topic;

Identifies gaps and provides directions for future research

Comprehensiveness depends on time/scope constraints No formal quality appraisal required Graphs, tables, and data representations, e.g. interactive data visualizations / maps Define quantity and quality of available literature based on relevant facets
Meta-analysis Statistically combines the results of quantitative studies on a topic to create a larger and more complete picture of the results Comprehensive and exhaustive search required

Formal quality appraisal is required;

Use appraisal to determine inclusion/exclusion of studies, overall quality of studies included, and sensitivity analyses

Statistics, graphs, tables, and narrative

Requires homogeneity of included studies for analyses to take place;

Statistical analysis of effect size

Mixed methods review

Synthesize qualitative and quantitative data to develop overarching conclusions;

Typically uses systematic review, comprehensive search methods

Uses either a comprehensive systematic review search strategy to retrieve all studies, or multiple comprehensive search strategies to retrieve quantitative and also qualitative studies

Formal quality appraisal is required;

Either use one appraisal tool (MMAT) or separate appraisal tools with comparable criteria to combine for final synthesis

Graphs, tables and narrative;

Goal is synthesizing qualitative and quantitative information

May characterize, compare and contrast, or identify gaps in different literature types (quantitative and/or qualitative)
Qualitative review

Integrate and compare results from qualitative studies;

Aim is to identify frequently occurring themes or constructs within and/or across studies

Comprehensiveness varies;

May use selective sampling only

Appraisal methods typically serve to mediate messages rather than for determining  inclusion/exclusion of studies Qualitative, narrative synthesis

Thematic analysis;

May include conceptual models

Rapid review

An expedited collection, assessment and synthesis of studies on a topic to inform policy or practice;

Uses abbreviated (and transparently reported) elements of systematic review methods adapted for a shorter timeline

Comprehensive search not required

Formal quality appraisal is required;

Use a time-limited formal appraisal method

Tables, narrative Define the quantity, quality, and direction of the literature
Scoping review

Provide an initial exploratory analysis of nature, size, and scope of research on a broad (or multiple related) topic/s not yet examined;

Identify what is known on a topic and directions for future research

Comprehensive and exhaustive search;

Typically includes grey literature

Formal quality appraisal not required Tables, narrative

Describe the quantity, quality, size, scope and types of available literature on a topic;

Often leads to future systematic reviews

State-of-the-art review

Focuses on recently published literature to assess current issues
Contrasts with retrospective or current approaches;

Highlights new ideas, gaps or points to future research

Comprehensive and exhaustive search of current literature Formal quality appraisal not required Tables, narrative Describes current state of knowledge on a topic and priorities for future research
Systematic review

Identify and synthesize research on a focused topic;

Uses pre-established, replicable methods for search, appraisal, and synthesis of literature

Comprehensive and exhaustive

Formal quality appraisal is required;

Use formal critical appraisal methods to determine the inclusion/exclusion of studies and quality of studies included

Tables, narrative Define what is known, unknown, or uncertain and provide recommendations for practice and/or future research
Systematic search and review

A comprehensive search, analysis, and synthesis of material from diverse sources;

Typically seeks to answer a broad question and provide best evidence

Comprehensive and exhaustive May include formal quality appraisal Tables, narrative Define what is known, provide recommendations for practice, discuss limitations
Systematized review

Describes most cases in which graduate students conduct an evidence synthesis;

Uses abbreviated (and transparently reported) elements of systematic review methods adapted for a shorter timeline

Elements of comprehensive and exhaustive search

May include quality appraisal;

May use a time-limited formal appraisal method

Tables, narrative

Define what is known, unknown, or uncertain about a topic;

Acknowledges procedural limitations

Umbrella review

A systematic review of systematic reviews;

Compiles and synthesizes evidence from multiple systematic reviews on a broad topic in which there are multiple differing conclusions / summaries

Comprehensive and exhaustive search is required;

Search looks for systematic reviews and other evidence synthesis, not primary studies

Formal quality appraisal is required;

Appraisal method evaluates quality of studies within each review as well as the overall systematic review/evidence synthesis

Graphs, tables, narrative Define what is known, unknown, or uncertain and provide recommendations for practice and/or future research

Table adapted from: Grant, M. J., & Booth, A. (2009). A typology of reviews: An analysis of 14 review types and associated methodologies. Health Information and Libraries Journal, 26(2), 91–108. https://doi.org/10.1111/j.1471-1842.2009.00848.x PMID: 19490148


Which review is right for you?

  • Right review 
    • A web-based tool designed to help researchers select the right review type based on a series of questions.
  • Systematic Review Decision Tree 
    • This chart from Cornell University Library can help you decide between a literature review, rapid review, scoping review, systematic review, umbrella review, and a meta-analysis.

What is a Systematic Review?

Evidence synthesis refers to any method of identifying, selecting, and combining results from multiple studies.

The term "systematic review" can be confusing, as there are a couple of things that could be meant.

"Systematic Review" can be a broad term meant to encompass all systematically-designed studies that review the evidence on a particular topic. However, it can also refer to a specific type of systematically-designed study that reviews the evidence on a particular topic. Depending on your question and resources, you may actually perform a meta-analysis, scoping review, rapid review, or a mapping review - all considered to be types of systematic reviews.